Publications

Original Articles

Khan ZA, Boscolo E, Picard A, Psutka S, Melero-Martin JM, Bartch TC, Mulliken JB, Bischoff J. 2008, Multipotential stem cells recapitulate human infantile hemangioma in immunodeficient mice, J. Clin Invest 118: 2592-2599. [Epub ahead of print]

Melero-Martin JM, De Obaldia ME, Kang S-Y, Khan ZA, Yuan L, Oettgen P, Bischoff J. 2008; Engineering vascular networks in vivo with human postnatal progenitor cells isolated from blood and bone marrow, Circ Res. 103: 194-202. [Epub ahead of print]

Yang JH, Wylie-Sears J, Bischoff J. 2008; Opposing Actions of Notch1 and VEGF in Post-natal Cardiac Valve Endothelial Cells. Biochem Biophys Res Comm, Jul 19. [Epub ahead of print]

  Xiao Wu, M. William Lensch, Jill Wylie-Sears, George Q. Daley and Joyce Bischoff. Hemogenic Endothelial Progenitor Cells Isolated from Human Umbilical Cord Blood. Stem Cells. 2007;25;2770-2776.

  Juan M. Melero-Martin, Zia A. Khan, Arnaud Picard, Xiao Wu, Sailaja Paruchuri, Joyce Bischoff. In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Blood. 2007;109:4761-4768.

  Sailaja Paruchuri, Jeong-Hee Yang, Elena Aikawa, Juan M. Melero-Martin, Zia A. Khan, Stavros Loukogeorgakis, Frederick J. Schoen, Joyce Bischoff. 2006, Human Pulmonary Valve Progenitor Cells Exhibit Endothelial/Mesenchymal Plasticity in Response to Vascular Endothelial Growth Factor-A and Transforming Growth Factor-ß2. Circ. Res. 2006;99;861-869.

  Zia A. Khan, Juan M. Melero-Martin, Xiao Wu, Sailaja Paruchuri, Elisa Boscolo, John B. Mulliken, and Joyce Bischoff. 2006, Endothelial progenitor cells from infantile hemangioma and umbilical cord blood display unique cellular responses to endostatin. Blood 108:915-921.

 Yu Y, Fuhr J, Boye E, Gyorffy S, Soker S, Atala A, Mulliken JB, and Bischoff J. 2006, Mesenchymal Stem Cells and Adipogenesis in Hemangioma Involution. Stem Cells Express Feb 2, 2006 epub ahead of print.

 Lee YM, Cope JJ, Ackermann GE, Goishi K, Armstrong EJ, Paw BH, Bischoff J. 2006; Vascular endothelial growth factor signaling is required for cardiac valve formation in zebrafish. Developmental Dynamics 235:29–37.

 Yu Y, Wylie-Sears J, Boscolo E, Mulliken JB, and Bischoff J. 2005, Genomic imprinting of IGF2 is maintained in infantile hemangioma despite its high level of expression.  Mol Med. 2004 Jul-Dec; 10(7-12):117-23.

 Yu Y, Moulton KS, Khan MK, Vineberg S, Boye E, Davis VM, O’Donnell PE, Bischoff J, Milstone DS. 2004; E-Selectin is Required for the Anti-Angiogenic Activity of Endostatin. , 2004; PNAS 101(21):8005–8010.

 Wu X, Rabkin-Aikawa E, Guleserian KJ, Perry TE, Masuda Y, Sutherland FWH, Schoen FJ, Mayer JE, Jr. Bischoff J. 2004; Tissue-engineered microvessels on three-dimensional biodegradable scaffolds using human endothelial cell progenitor cells. Am J Phys. Heart and Circulatory Physiology, 287: H480-H487.

 Yu Y, Flint A, Mulliken JB, Wu JK, Bischoff J. 2004; Endothelial progenitor cells in infantile hemangioma. Blood, 103: 1373-1375.

Li Q, Yu Y, Bischoff J, Mulliken JB, Olsen BR. 2003; Differential expression of CD146 in tissues and endothelial cells dervied from infantile hemangioma and normal human skin. J. Pathol. 201: 296-302.

 Dvorin EL, Jacobson J, Roth SJ, Bischoff J. 2003; Human pulmonary valve endothelial cells express functional adhesion molecules for leukocytes. J. Heart Valve Disease, 12: 617-624.

 Dvorin EL, Wylie-Sears J, Martin DP, Bischoff J. 2003; Quantitative evaluation of endothelial cell proliferation and differentiation on PGA/P4HB (poly-glycolic acid/poly-4-hydroxybutyrate scaffold in response to VEGF and TGF-ß1. Tissue Engineering, 9: 487-493.

Perry TE, Kaushal S, Sutherland FWH, Gulerserian KJ, Bischoff J, Sacks M, Mayer JE, Jr. 2003 Bone marrow as a cell source for tissue engineering heart valves. Ann. Thorac. Surg. 75: 761-767.

 Johnson EN, Lee YM, Sander TL, Rabkin E, Schoen FJ, Kaushal S, Bischoff J. 2003; NFATc1 mediates VEGF-induced proliferation in human pulmonary valve endothelial cells. J. Biol. Chem. 278: 1686-1692.

 Yu, Y, Flint, A. Dvorin EL, Bischoff, J. 2002; AC133-2: A novel isoform of human AC133 stem cell antigen. J. Biol. Chem. 277: 20711-20716.

 Yu, Y, Varughese, J, Brown, LF, Mulliken, JB, Bischoff, J. 2001; Increased Tie2 expression, enhanced response, and dysregulated angiopoietin-2 expression in hemangioma-derived endothelial cells. Am. J. Path. 159: 2271-2280.

 Boye E, Yu Y, Paranya G., Mulliken JB, Olsen BR, Bischoff J. 2001; Clonality and altered behavior of endothelial cells from hemangioma, J. Clin. Invest. 107: 745-752.

 Paranya G, Vineberg S, Dvorin, E. Kaushal S, Roth SJ, Rabkin E, Schoen FJ, Bischoff J. 2001; Aortic valve endothelial cells undergo TGF-beta-mediated and non-TGF-beta-mediated transdifferentiation in vitro. Am. J. Pathol.159: 1335-1343.

 Kaushal S, Emiel G, Guleserian KJ, Shapira OM, Perry T, Sutherland FW, Rabkin E, Moran AM, Schoen FJ, Atala A, Soker S, Bischoff J, Mayer J. 2001; Functional small diameter neovessels created using endothelial progenitor cells expanded ex vivo. Nature Medicine, 7: 1035-1040.

Luo J, Kato M, Wang H, Bernfield M, Bischoff J. 2001; Heparan sulfate and chondroitin sulfate proteoglycans inhibit E-selectin binding to endothelial cells. J. Cell. Biochem. 80: 522-531.

Tomilinson J, Wang JL, Barksy SH, Lee MC, Bischoff J, Nguyen, M. 2000; Human colon cancer cells express multiple glycoprotein ligands for E-selectin. International Journal of Oncology 16: 347-353.

Smith LEH, Shen W, Peruzzi C, Soker S, Kinose F, Xu X, Robinson G, Driver S, Bischoff J, Zhang B, Schaeffer J, Senger D. 1999; Regulation of VEGF-dependent retinal neovascularization by IGF-1 Receptor. Nature Med.5: 1390-1395

Luo J, Paranya G, Bischoff J. 1999; Non-inflammatory expression of E-selectin is regulated by cell growth. Blood 93: 3785-3791.

Luo J, Lin J, Paranya G, Bischoff J. Angiostatin selectively upregulates E-selectin in proliferating endothelial cells. 1998; Biochem Biophys Res Comm 245, 906-911.

Razon M J, Kräling, BM, Mulliken JB, Bischoff, J. Increased apoptosis coincides with onset of involution in infantile hemangioma. 1998; Microcirculation 5: 189-195.

Kräling BM, Bischoff J. A simplified method for growth of human microvascular endothelial cells results in decreased senescence and continued responsiveness to cytokines and growth factors. 1998; In Vitro Cellular and Developmental Biology 33: 308-315.

Nguyen M, Corless C L, Kräling B, Chanh T, Atha T, Bischoff J, Barsky, SH Vascular expression of E-selectin is increased in estrogen receptor negative breast cancer and is probably mediated by IL-1a. 1997; Am J Path 150: 1307-1314.

Bischoff J, Brasel C, Kräling BM, Vranovska K. E-selectin is upregulated in growing endothelial cells in vitro. 1997; Microcirculation 4: 279-288.

Kraling BM, Razon M J, Boon LM, Zurakowski D, Seachord C, Darveau RP, Mulliken, JB, Corless CL, Bischoff J. E-Selectin is present in proliferating endothelial cells in human hemangiomas. Am J Path 1996; 148: 1181-1191.

Zund G, Nelson DP, Neufeld EJ, Dzus, AL, Bischoff J., Mayer JE, Colgan SP Hypoxia enhances stimulus-dependent induction of E-selectin in aortic endothelial cells. 1996; Proc Natl Acad Sci USA 93: 7075-7080.

Budson AE, Ko L, Brasel C, Bischoff, J. The angiogenesis inhibitor AGM-1470 selectively increases E-selectin 1996; Biochem Biophys Res Comm 225: 141-145.

Bischoff J, Brasel C. Regulation of P-selectin by tumor necrosis factor-a. Biochem Biophys Res Comm 1995; 210: 174-180.

Nguyen M, Strubel NA, Bischoff J. A role for sialyl Lewis-X/A glycoconjugates in capillary morphogenesis. Nature 1993; 365: 267-269.

Strubel NA, Nguyen M, Kansas GS, Tedder TF, Bischoff J. Isolation and characterization of a bovine endothelial cell cDNA encoding a functional homolog of human P-selectin. Biochem Biophys Res Comm 1993; 192: 338-342.

Nguyen M, Folkman J, Bischoff J. 1-Deoxymannojirimycin inhibits capillary tube formation in vitro. J Biol Chem 1992; 267: 26157-26165.

Bischoff J, Moremen K, Lodish HF. Isolation, characterization, and expression of cDNA encoding the rat liver endoplasmic reticulum a-mannosidase. J Biol Chem 1990; 265: 17110-17117.

Bischoff J, Libresco S, Shia MA, Lodish HF. The H1 and H2 polypeptides associate to form the asialoglycoprotein receptor in human hepatoma cells. J Cell Bio 1988; 106: 1067-1074.

Bischoff J, Lodish HF. Two asialoglycoprotein receptor polypeptides in human hepatoma cells. J Biol Chem 1987; 262: 11825-11832.

Bischoff J, Liscum L, Kornfeld R. The use of 1-deoxymannojirimycin to evaluate the role of various alpha-mannosidases in oligosaccharide processing in intact cells. J Biol Chem 1986; 261: 4766-4774.

Bischoff J, Kornfeld, R. The soluble form of rat liver alpha-mannosidase is immunologically related to the endoplasmic reticulum membrane alpha-mannosidase. J Biol Chem 1986; 261: 4748-4765.

Bischoff J, Kornfeld, R. The effect of 1-deoxymannojirimycin on rat liver alpha-mannosidases. Biochem Biophys Res Comm 1984; 125: 324-331.

Bischoff J, Kornfeld, R. Evidence for an alpha-mannosidase in endoplasmic reticulum of rat liver. J Biol Chem 1983; 258: 7907-7910.

Reviews

Bischoff J. Hemangioma – A Model System to Study Growth and Regression of Blood Vessels.  In Microvascular Research:  Biology and Pathology, 2005, Ed. D. Shepro, Elsevier Inc., Amsterdam, The Netherlands [book web site]

 Armstrong, EJ., Bischoff J., Heart Valve Development Endothelial Cell Signaling and Differentiation. 2004; Circ Res. 95:459-470.

Bischoff J. Monoclonal Expansion of Endothelial Cells in Hemangioma: An Intrinsic Defect with Extrinsic Consequences? 2002; Trends in Cardiovascular Medicine, 12: 220-224.

Bischoff J. Cell adhesion molecules in angiogenesis. 1997; J. Clin. Invest. 3: 373-376.

Bischoff J. Approaches to studying cell adhesion molecules in angiogenesis. 1995; Trends in Cell Biology 5(2):69-74.

Bischoff J. Functions of E-selectin. 1994; Trends Glycosciences and Glycotechnology 6(31):351-365.

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